Princess Mononoke - Ecological disasters create monsters. Monsters fed from polluted chi energy.
Ghostbusters - Demon hunters/exterminators, problem solvers.
Spirited Away - some spirits/monsters seek nonviolent resolution and may even end up helping in fight against the spheres. Memories of the long past chain spirits to Ketoru, preventing them from finding peace and getting them mixed up in situations with the living.
2001: A Space Odyssey - Spheres are like the monolith, having an effect on the human population (re-animate dead, mutatation, causing changes to physical reality, blending physical and spiritual world, opening dimensional gateways)
A Princess of Mars - Planet is post-apocalyptic society in the far future that's fallen into barbarism. Barbarian warlords rule the day.
Smallville - Humans are undergoing the effects of the Sphere's mutational and warping powers (much like kryptonite affected the citizens of Smallville). Cases of "infection" crop up that cause problems for our heroes.
Psionics - The base type of magic. No purely-fantasy based magic exists. Rip out the spells in R&R, replace with psionics (in-game PCs would refer to it as "magic" just the same).
Re-animation of the dead - Zombies, wights, skeletons that roam and attack (or sometimes don't attack) without a base-alignment. Sometimes they even attack each other. They're more like terrain to be encountered--not an fighting force that can be organized.
Ancient technology - Level of technology is mainly barbarian/medieval but occassionally something form the long past is recovered--and ancient treasure. This could be something from our modern world or even more advanced that appears to be completely "magical" to the people of Ketoru.
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